RIVA2018_LG

 

RIVA 2018

May 13-18, 2018 | Riva del Garda, Italy
Booth #3

The 42nd International Conference Symposium on Capillary Chromatography (ISCC) jointly organized with the 15th GCxGC Symposium, will be held this year in Riva del Garda, Italy. This year particular emphasis will be directed to all Comprehensive Separation Technologies and MS Hyphenation and to capillary chromatography and 2D GC with various forms of MS from unit-mass to high resolution, and from single to hybrid analyzers. 

 

LECO Vendor Seminar

Tuesday, May 15th | 15:45-16:45 | Room 300
Speaker: Jef Focant, University of Liege
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GC×GC-(HR)TOFMS : A KEY PLAYER IN YOUR TOOL BOX FOR MEDICAL APPLICATIONS
GC×GC-(HR)TOFMS has reached maturity and can now be used to solve routine complex Separation Science issues. This is particularly true for several medical applications that require non-targeted screening of biological markers of interest either for population screening or better understanding of specific biological pathways. However, this increase of analytical resolution comes with an increase of system and data complexity. This creates a critical need for adequate method optimization and quality control (QC) protocols to ensure the proper use of the analytical instrument, and robust data processing flow for interpretation. In that context, examples of the use of thermal desorption (TD) and solid-phase microextraction (SPME) GC×GC-(HR)TOFMS will be highlighted in the field of respiratory diseases. SPME-GC×GC-HRTOFMS analyses of volatile profiles of bronchoalveolar lavage fluid (BALF) were carried out. Collecting BALF is a widely performed medical procedure that provides important information about immunologic, inflammatory, and infectious processes in the airways. Pooled BALF samples were used to create a QC sample subsequently used for method development and for the implementation of a QC protocol for non-targeted analysis of volatile mixtures in arrays of biological matrices. TD-GC×GC-HRTOFMS analyses of volatile organic compounds (VOCs) from breath were further successfully carried out as a non-invasive diagnostic approach to differentiate between different inflammatory profiles. The extraction of the volatile profile of exhaled breath of patients following dedicated data (pre-)processing and statistical treatments allowed the discrimination according to their respective phenotypes. These studies aim to provide guidance for the establishment of robust GC×GC-TOFMS strategies for non-targeted analysis in medical applications.

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LECO Featured Products

Want to learn more? Click here to review our white papers on Separation Science Mass Spectrometry.

 

LECO Oral Presentations

Monday, May 14th, 12:40 pm | Le.17
COMPREHENSIVE NON-TARGET CHARACTERIZATION OF EXPOSOME SAMPLES USING GCXGC AND HIGH RESOLUTION MASS SPECTROMETRY
Lorne Fell | LECO Corporation, United States

Monday, May 14th, 17:10 pm | KNLe.05
A GCXGC-TOFMS METHOD FOR THE QUANTIFICATION OF 54 ALLERGENS IN FRAGRANCE MATERIALS 
Sebastiano Pantò | LECO European Application and Technology Center, Germany

Tuesday May 15th, 14:20 pm | Le.34 
A DIRECT COMPARISON OF THERMAL MODULATION AND TWO MODES OF FLOW MODULATION FOR GCXGC
David J. Borton |LECO Corporation, United States

 

LECO Poster Presentations

E.09 IDENTIFICATION OF FRAGRANCE ALLERGENS BY GC-TOF ANALYSIS
Federica Vento | Chromaleont S.r.L., Italy

K.05 SMOKER'S AND NON-SMOKER'S URINE COMPARISON USING COMPREHENSIVE TWO DIMENSIONAL GAS CHROMATOGRAPHY-HIGH PERFORMANCE TIME-OF-FLIGHT MASS SPECTROMETRY
David Alonso  | LECO Corporation, United States

K.08 CRYOGENICALLY-MODULATED COMPREHENSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY-HIGH RESOLUTION TIME-OF-FLIGHT MASS SPECTROMETRY: DETAILED QUALITATIVE PROFILING OF THE UNSAPONIFIABLE FRACTION OF VEGETABLE OILS
Ivan Aloisi | Dipartimento di Scienze Chimiche, Italy

K.10 AROMA PROFILING OF COFFEE WITH GC, GCXGC, AND TOFMS
Joe Binkley  | LECO Corporation, United States

K.39 COMPREHENSIVE GCxGC–HR TOFMS: ON THE WAY TOWARDS FULL CHEMICAL CHARACTERIZATION OF PETROLEUM PRODUCTS
Tomas Kovalczuk | LECO Instrumente Plzen, Czech Republic

K.42 GCXGC-TOF MS ANALYSIS OF PETROCHEMICAL SAMPLES: FINE TUNING OF SEPARATION
Tomas Kovalczuk | LECO Instrumente Plzen, Czech Republic

K.49 CHARACTERIZATION OF CRUDE OIL REFINING PRODUCTS USING A GCXGC-HRMS WITH AN INTEGRATED DIRECT INLET PROBE
Juergen Wendt | LECO European Application and Technology Center, Germany

K.72 OPTIMIZING GCXGC PARAMETERS FOR PETROLEUM ANALYSIS USING A FREE WEB BASED TOOL
Christina N. Kelly | LECO Corporation, United States

K.73 DETERMINING TERPENE PROFILES OF CANNABIS STRAINS USING GC AND GCXGC WITH HIGH PERFORMANCE TOFMS
David Alonso | LECO Corporation, United States

K.77 A COMPARISON OF PAH LEVELS IN USED ENGINE OILS BY GC-TOFMS AND GCXGC TOF-MS
Christina Kelly | LECO Corporation, United States

K.81 CHARACTERIZATION OF VOLATILE AND SEMI-VOLATILE ORGANIC COMPOUNDS PROFILE FROM WINE SAMPLES PROVIDED FROM A SMALL LOCAL PRODUCER BY SPME-GCXGC-TOFMS AND HS-SPME-GCXGC-TOFMS
Aurel M. Toderici | Dept. of Research and Development - Natl. R&D Inst. for Cryogenics and Isotopic Technologies - ICSI, Romania;
Fac. of Appl. Chem. and Mat. Sci. SIMONA Dept. - Politehnica University of Bucharest, Romania 

K.82 PROFILE OF VOLATILE AND SEMI-VOLATILE ORGANIC COMPOUNDS FROM ALCOHOLIC DISTILLATED BEVERAGE SAMPLES PROVIDED FROM A BRANDY LOCAL PRODUCER BY SPME-GCXGC-TOFMS AND HS-SPME-GCXGC-TOFMS
Diana StegarusDept. of Research and Development - Natl. R&D Inst. for Cryogenics and Isotopic Technologies, Romania 

P.02 FLAVOR ANALYSIS OF HOT STEEPED MALT FOR BEER BREWING BY GC-MS
Joe Binkley | LECO Corporation, United States

P.19 INVESTIGATION OF EXTRACTED AND LEACHED ANALYTES FROM PACKAGING MATERIALS WITH GC-TOFMS
Tomas Kovalczuk | LECO Instrumente Plzen, Czech Republic