Medical Diagnosis using Breath Analysis and GCxGC-TOFMS: Optimizing Data for Accurate Treatment

At our ASMS breakfast seminars, Jean-François (Jef) Focant, Head of the Department of Chemistry and Director of the Organic and Biological Analytical Chemistry group at the University of Liège, Belgium, spoke about using our Pegasus® BT 4D and Pegasus® GC-HRT 4D for GCxGC-TOFMS on the breath of asthma patients to improve asthma treatment. Before diving into the blood and sputum, Jef first educated us on the importance of optimizing your data.

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Topics: Mass Spectrometry

ASMS in Review: Frank Dorman, Penn State

Frank Dorman, an Associate Professor of Biochemistry and Molecular Biology at Penn State University, spoke at our ASMS breakfast seminar about his experience using our Pegasus BT 4D benchtop GCxGC-TOFMS to analyze environmental contamination in the Susquehanna river. Due to the increasing chemical complexity of the environment, GCxGC-TOFMS with its Non-Targeted compound analysis is the ideal technology for these intricate samples.

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Topics: Mass Spectrometry

Did You Miss Us at ASMS? Presentations Are Now Available

At LECO we understand your lab’s problems and how to solve them, which is why we offer a wide array of reliable and innovative separation science solutions so you can dig deeper into your samples. Some of our solutions were recently on display at ASMS.

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Topics: Mass Spectrometry

Take Your GC-MS Analysis One Step Further

What if you could take your GC-MS analysis one step further by easily adding a second dimension of separation? Our new FLUX™ GCxGC flow modulator uses a diverting flow technique (rather than industry-standard thermal modulation), eliminating the need for costly cryogens, and making GCxGC more cost-effective and routine to the everyday analyst.

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Topics: Mass Spectrometry

Of Fireworks and Tourism: GCxGC-HRMS Analysis of Summer Impacts on Lake Michigan Water Quality

Fireworks are a staple of America’s Independence Day celebrations. It is estimated that 16,000 fireworks displays are held in the United States each year and American consumers will spend more than $1 billion in firework sales to mark the holiday! Beyond a big bang and bright lights, how do these fireworks affect the environmental world around them? LECO’s world headquarters are located in Saint Joseph, Michigan, a beach town on Lake Michigan where fireworks are a prominent backdrop to the 4th of July celebration. Last summer, our applications lab thought it would be a worthwhile and interesting experiment to test the water surrounding the firework launch spot to explore if there were any short-term environmental impacts. The influx of tourists to the Lake Michigan beaches during the holiday is sure to contribute chemicals from personal care products (sunscreen and insect repellent) to the water as well. Evaluating these potential contaminants surrounding the July 4th holiday was the objective of this study.

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Topics: Mass Spectrometry

Come Meet Us on the Road—Quality Assurance and Safety Seminar Series!

We’re excited to be partnering with SCIEX to take part in their West Coast Roadshow series! This FREE Quality Assurance and Safety Seminar series will take place in California, comprising of three different stops along the way; Palm Desert, Torrance, and Emeryville. Attendees will have the chance to learn how to tackle their analytical testing challenges while keeping up with emerging contaminants and residue regulations. Our portion of the series will be presented by LECO’s Separation Science Product Manager, Lorne Fell, who will detail the advantages of GC and GCxGC MS for cannabis, food, and environmental testing.

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Topics: Mass Spectrometry

Heading to Pittcon? Don't Miss These LECO Happenings

There are many exciting things happening at Pittcon this year! This year’s Pittcon is taking place in Philadelphia, Pennsylvania from March 17 to the 21—the show brings together the latest technologies and research in laboratory science. We’ll be at booth #3127, stop by for visit, where you’ll be able to discuss your application with us, and we will work with you to find the right solution for your laboratory! Our GC-MS solutions offer industry-leading sensitivity, seamless data handling, and high sample throughput, giving you everything you need to dissect your most demanding applications and explore all that is in your sample faster than ever before. On display will be our Pegasus HRT+ 4D High Resolution TOFMS and our Pegasus BT 4D GCxGC-TOFMS featuring our new FLUX flow modulator

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Topics: Mass Spectrometry

LECO and Restek Collaborate in Worldwide Supply Agreement

LECO Corporation, a global leader in analytical instrumentation and mass spectrometers, and Restek Corporation, a leading independent developer and manufacturer of chromatography products, are pleased to announce their recent expanded collaboration. This agreement will allow LECO customers access to a core set of Restek consumables—streamlining the customer’s setup and offering the convenience of one simplified combined package. The consumables offering provides the perfect match of GCxGC consumables to operate your LECO instrument.

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Topics: Mass Spectrometry

LECO Releases New Flow Modulator—FLUX™

LECO is pleased to introduce a new FLUX™ flow modulator option for routine GCxGC analysis. While LECO’s traditional thermal modulation alternative is still available and provides for the highest sensitivity, the FLUX flow modulator is a cost-effective option that makes GCxGC more accessible and easy to use.

The new flow modulator’s extraordinarily simple design is based on the principles of John Seeley et al. This straightforward design makes the flow modulator easy for the user to set up and start performing GCxGC analysis. The flow-based modulator is ideal for users who want to perform robust GCxGC analysis, but do not need the sensitivity of standard quad jet thermal modulation. Ideal samples are complex, but relatively concentrated. Our early users program has given us tremendously positive feedback.


Another advantage of the FLUX flow modulator is that it does not require cryogens to carry out GCxGC, saving the user time and resources in their lab. Method development is also simplified, as there are only two parameters for the user to manage; the flows are handled by software so the user does not have to set these themselves. The FLUX flow modulator is available for purchase with our Pegasus® BT 4D, and also for existing Pegasus BT owners who wish to upgrade their system to a GCxGC with FLUX.

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Topics: Mass Spectrometry

Application Spotlight: StayClean Ion Source Stability

Our innovative separation science solutions work to solve the common problems you face in your laboratory while also providing the sensitivity, resolving power, accuracy, deconvolution, and speed you need to discover what else is in your sample. Our GC-TOFMS and GCxGC instrumentation can answer key questions in your most complex samples and pioneer high sample throughput, so you can streamline your analysis.

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Topics: Mass Spectrometry