GC-MS Water Analysis: Why is TOF Better than Quadrupole?

Did you see the recent Q&A on GC-MS Water Analysis on LCGC? David Benanou, of Veolia Research and Innovation, challenged a gas chromatography—time-of-flight mass spectrometry (GC–MS-TOF) instrument (our Pegasus BT) to its limit of quantification by injecting very dilute solutions of compounds beyond their odor threshold concentration.

With the Pegasus BT, a quantitation limit of 2 pg per liter was required to obtain the full mass spectrum, whereas a GC–MS quadrupole instrument required 100 pg per liter to obtain the same result. LCGC recently sat down with David, an expert of analytical chemistry, to further discuss the advantages of TOF analysis. 

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